Forskohlin works to increase cyclic AMP, which helps the body mobilize body fat for use as energy. Clinical studies show Forslean helps reduce body fat and increase lean muscle mass.
Coleus forskohlii, is a component of the mint family of herb. Its scientific name is Plectran thus barbatus. The root extract of the plant include a compound called forskolin. As such, coleus forskohlii and forskolin are often used interchangeably. Coleus Forskohli Forslean Traditionally Used In Ayurvedic Forskohlii Extract Natural Supplements Ayurvedic Medicines.
Forskohlin is known as a compound with versatile biological actions based on its ability to stimulate adenylate cyclase and cyclic AMP levels. Typically, an increase in cyclic AMP leads to subsequent activation of protein kinase. Protein kinase has been shown to activate the hormone sensitive lipase which is involved in the breakdown of triglycerides, known as building blocks of fatty tissue.
The other factor relevant to the weight loss mechanism of Forskohlin involves its thyroid stimulating action, comparable in strength to thyrotropin or TSH2. The thyroid stimulating action of Forskohlin may also contribute to the increase in the metabolic rate and thermogenesis.
Forskohlin may also be involved in regulating insulin secretion3. Insulin, although well recognized for its metabolism of carbohydrates, is also involved in the metabolism of fats and proteins that are major contributors to body composition
A clinical study with Forslean® showed that a dose that provides 25mg of Forskohlin twice a day could help improve overall body composition by increasing bulk due to lean body mass while decreasing bulk due to body fat.
The use of Forslean® helps to maintain a healthy body composition coleus forskohlii forslean ayurvedic medicines and helps in weight loss Supplement.
Forslean® potentially benefits not only overweight people but also those individuals who are actively involved in athletic training or body building, seeking to attain a higher lean body mass to body fat ratio.
We strongly recommend the use of a sensible diet along with an exercise regimen of 30-45 minutes duration for effective weight management. Natural products such as Forslean® may enhance such measures and help to achieve the desired results.
Forskohlin is valued as an acetylate cyclase activator. Adenylate cyclase is the enzyme involved in the production of Cyclic Adenosine Monophosphate (cAMP), (a significant biochemical agent involved in metabolic processes), from the high energy molecule, ATP (Adenosine triphosphate).
It facilitates the action of "primary messengers" or various hormonal and bioactive substances in the body.
The role of cyclic AMP is indispensable to many body functions. Cyclic AMP induces a chain of biochemical events that trigger metabolic processes and diet induced thermogenesis3, thereby providing the means to maintain a healthy body composition and lean body mass levels.
Lean body mass is constituted by the muscles, vital organs, bone and bone marrow, connective tissue and body water. The percentage of lean body mass to fat not only determines the body's aesthetic appearance, but more importantly, it is also an index of physical fitness, health status, susceptibility to disease and premature mortality.